How much is desvenlafaxine (Pristiq)?
Real cash prices near you, ranked by what you pay.
What does it cost without insurance?
The lowest cash price for each strength, no insurance needed.
| Strength | Where | Pharmacies pay | Cash price |
|---|---|---|---|
| ER 25 mg tablet30 tablets | Mark Cuban Cost Plus DrugsMail order | Pharmacies pay about $11.61 | $21.90 |
| ER 50 mg tablet30 tablets | Mark Cuban Cost Plus DrugsMail order | Pharmacies pay about $11.98 | $18.46 |
| ER 100 mg tablet30 tablets | Mark Cuban Cost Plus DrugsMail order | Pharmacies pay about $12.40 | $16.37 |
Mail order, store generic lists and drug makers’ own prices, checked November 8, 2026. “Pharmacies pay” is roughly what pharmacies themselves pay for it, from Medicare’s national price survey (October 21, 2026).
What else should I know?
Straight answers, no medical advice.
Which strength do I need?
The one on your prescription label. Prices change with strength, so we never guess. If you aren’t sure, ask your pharmacist.
Is there a generic?
Yes. Desvenlafaxine is the generic for Pristiq.
Does the drug maker sell it for less?
TrumpRx savings coupon: $200.10 for 30 tablets of ER 25 mg tablet. See the program
TrumpRx savings coupon: $200.10 for 30 tablets of ER 50 mg tablet. See the program
TrumpRx savings coupon: $200.10 for 30 tablets of ER 100 mg tablet. See the program
Can I ask in my chat instead?
Yes. Add EveryCard Rx to Claude or ChatGPT, then ask “How much is my desvenlafaxine near me?”